topologyGSA (1.4.6)

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Gene Set Analysis Exploiting Pathway Topology.

http://cran.r-project.org/web/packages/topologyGSA

Using Gaussian graphical models we propose a novel approach to perform pathway analysis using gene expression. Given the structure of a graph (a pathway) we introduce two statistical tests to compare the mean and the concentration matrices between two groups. Specifically, these tests can be performed on the graph and on its connected components (cliques).

Maintainer: Gabriele Sales
Author(s): Sofia Massa, Gabriele Sales

License: GPL-3

Uses: fields, graph, gRbase
Reverse suggests: graphite, simPATHy

Released 11 months ago.


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