BIGL (1.4.1)

0 users

Biochemically Intuitive Generalized Loewe Model.

Response surface methods for drug synergy analysis. Available methods include generalized and classical Loewe formulations as well as Highest Single Agent methodology. Response surfaces can be plotted in an interactive 3-D plot and formal statistical tests for presence of synergistic effects are available. Implemented methods and tests are described in the article "BIGL: Biochemically Intuitive Generalized Loewe null model for prediction of the expected combined effect compatible with partial agonism and antagonism" by Koen Van der Borght, Annelies Tourny, Rytis Bagdziunas, Olivier Thas, Maxim Nazarov, Heather Turner, Bie Verbist & Hugo Ceulemans (2017) .

Maintainer: Maxim Nazarov
Author(s): Heather Turner, Annelies Tourny, Olivier Thas, Maxim Nazarov, Rytis Bagdziunas

License: GPL-3

Uses: ggplot2, MASS, minpack.lm, numDeriv, progress, rgl, robustbase, scales, testthat, knitr, shiny, rmarkdown, DT

Released 5 months ago.

7 previous versions



  (0 votes)


  (0 votes)

Log in to vote.


No one has written a review of BIGL yet. Want to be the first? Write one now.

Related packages:(20 best matches, based on common tags.)

Search for BIGL on google, google scholar, r-help, r-devel.

Visit BIGL on R Graphical Manual.