FamEvent (1.1)

Simulation of Time-to-Event Family Data and Penetrance Estimation.


Generates time-to-event family data associated with mutated genes arising from various family study designs such as population-based, clinic- based, or multi-stage designs and provides functions to fit family data accounting for the study design and estimate age-dependent penetrance functions. It also provides carrier probabilities for those with missing genotypes and penetrance estimations are based on an Expectation-Maximization algorithm when genotypes are missing.

Maintainer: Yun-Hee Choi
Author(s): Yun-Hee Choi, Karen Kopciuk, Wenqing He, Laurent Briollais

License: GPL (>= 2.0)

Uses: kinship2, MASS, survival, truncnorm

Released almost 4 years ago.