GWsignif (1.1)

Estimating Genome-Wide Significance for Whole Genome Sequencing Studies, Either Single SNP Tests or Region-Based Tests.

The correlations and linkage disequilibrium between tests can vary as a function of minor allele frequency thresholds used to filter variants, and also varies with different choices of test statistic for region-based tests. Appropriate genome-wide significance thresholds can be estimated empirically through permutation on only a small proportion of the whole genome.

Maintainer: ChangJiang Xu
Author(s): ChangJiang Xu and Celia M.T. Greenwood

License: GPL (>= 2)

Uses: Does not use any package

Released over 3 years ago.