MLML2R (0.1.0)

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Maximum Likelihood Estimation of DNA Methylation and Hydroxymethylation Levels.

Maximum likelihood estimates (MLE) of the levels of 5-mC and 5-hmC in the DNA using information from BS-conversion, TAB-conversion, and oxBS-conversion methods. One can use information from all three methods or any combination of two of them. Estimates are based on Binomial model by Qu et al. (2013) and Kiihl et al. (2018, to appear).

Maintainer: Samara Kiihl
Author(s): Samara Kiihl [aut, cre], Maria Jose Martinez-Garrido [aut], Arce Domingo-Relloso [aut], Jose Bermudez [aut], Maria Tellez-Plaza [aut]

License: MIT + file LICENSE

Uses: microbenchmark, knitr, rmarkdown

Released 6 days ago.



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