MLML2R (0.3.3)

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Maximum Likelihood Estimation of DNA Methylation and Hydroxymethylation Proportions.

Maximum likelihood estimates (MLE) of the proportions of 5-mC and 5-hmC in the DNA using information from BS-conversion, TAB-conversion, and oxBS-conversion methods. One can use information from all three methods or any combination of two of them. Estimates are based on Binomial model by Qu et al. (2013) and Kiihl et al. (2019) .

Maintainer: Samara Kiihl
Author(s): Samara Kiihl [aut, cre], Maria Jose Martinez-Garrido [aut], Arce Domingo-Relloso [aut], Jose Bermudez [aut], Maria Tellez-Plaza [aut]

License: MIT + file LICENSE

Uses: microbenchmark, knitr, rmarkdown

Released about 1 month ago.

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