OSACC (1.0)

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Ordered Subset Analysis for Case-Control Studies.


Genetic heterogeneity can reduce the power for complex disease gene mapping since only a fraction of the cases in the collected dataset may carry a specific disease susceptibility allele. The Ordered Subset Analysis for Case-Control data (OSACC) program was designed to evaluate evidence for association in the presence of genetic heterogeneity. For a more detailed description of the method and results of an extensive simulation study based on different models of genetic heterogeneity. Please see Qin et. al.(2010), Ordered Subset Analysis for Case-Control Studies, Genetic Epidemiology 34(5), 407-417.

Maintainer: Xuejun Qin
Author(s): Xuejun Qin, Elizabeth R. Hauser, Silke Schmidt,(Center for Human Genetics, Duke University)

License: LGPL (>= 2.0)

Uses: Does not use any package

Released about 9 years ago.



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