RNOmni (0.7.1)

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Rank Normal Transformation Omnibus Test.


Genetic association tests that use the rank-based inverse normal transformation (INT). These tests are recommend for continuous traits with non-normally distributed residuals. INT-based tests robustly control the type I error in settings where standard linear regression does not. Moreover, INT-based tests dominate standard linear regression in terms of power. INT-based tests may be classified into two types: tests that directly transform the phenotype (D-INT) and tests that transform phenotypic residuals (I-INT). Our omnibus test (O-INT) adaptively combines D-INT and I-INT into a single robust and statistically powerful approach.

Maintainer: Zachary McCaw
Author(s): Zachary McCaw [aut, cre]

License: GPL-3

Uses: abind, foreach, plyr, Rcpp, ggplot2, reshape2, knitr, rmarkdown, cowplot

Released 9 months ago.

11 previous versions



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