SeqKat (0.0.4)

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Detection of Kataegis.

Kataegis is a localized hypermutation occurring when a region is enriched in somatic SNVs. Kataegis can result from multiple cytosine deaminations catalyzed by the AID/APOBEC family of proteins. This package contains functions to detect kataegis from SNVs in BED format. SeqKat reports two scores per kataegic event, a hypermutation score and an APOBEC mediated kataegic score. Upon publication of the paper describing the methods used in this package, a reference will be added here.

Maintainer: Paul C. Boutros
Author(s): Fouad Yousif, Xihui Lin, Fan Fan, Christopher Lalansingh

License: GPL-2

Uses: doParallel, foreach, doMC, testthat, knitr, rmarkdown

Released 7 months ago.



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