SubgrpID (0.11)

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Patient Subgroup Identification for Clinical Drug Development.

Function Wrapper contains four algorithms for developing threshold-based multivariate (prognostic/predictive) biomarker signatures via bootstrapping and aggregating of thresholds from trees, Monte-Carlo variations of the Adaptive Indexing method and Patient Rule Induction Method. Variable selection is automatically built-in to these algorithms. Final signatures are returned with interaction plots for predictive signatures. Cross-validation performance evaluation and testing dataset results are also output.

Maintainer: Xin Huang
Author(s): Xin Huang, Yan Sun, Saptarshi Chatterjee and Paul Trow

License: GPL-3

Uses: AIM, ggplot2, glmnet, Matrix, rpart, survival

Released about 3 years ago.



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