adoptr (0.2.3)

Adaptive Optimal Two-Stage Designs in R.

Optimize one or two-arm, two-stage designs for clinical trials with respect to several pre-implemented objective criteria or implement custom objectives. Optimization under uncertainty and conditional (given stage-one outcome) constraints are supported. See Pilz M, Kunzmann K, Herrmann C, Rauch G, Kieser M. A variational approach to optimal two-stage designs. Statistics in Medicine. 2019;113. for details.

Maintainer: Kevin Kunzmann
Author(s): Kevin Kunzmann [aut, cre], Maximilian Pilz [aut]

License: MIT + file LICENSE

Uses: glue, nloptr, testthat, knitr, rmarkdown, covr, vdiffr, rpact

Released 12 days ago.