frailtypack (3.0.3.2)
General Frailty Models: Shared, Joint and Nested Frailty Models with Prediction; Evaluation of FailureTime Surrogate Endpoints.
https://virginie1rondeau.wixsite.com/virginierondeau/softwarefrailtypack
http://cran.rproject.org/web/packages/frailtypack
The following several classes of frailty models using a penalized likelihood estimation on the hazard function but also a parametric estimation can be fit using this R package: 1) A shared frailty model (with gamma or lognormal frailty distribution) and Cox proportional hazard model. Clustered and recurrent survival times can be studied. 2) Additive frailty models for proportional hazard models with two correlated random effects (intercept random effect with random slope). 3) Nested frailty models for hierarchically clustered data (with 2 levels of clustering) by including two iid gamma random effects. 4) Joint frailty models in the context of the joint modelling for recurrent events with terminal event for clustered data or not. A joint frailty model for two semicompeting risks and clustered data is also proposed. 5) Joint general frailty models in the context of the joint modelling for recurrent events with terminal event data with two independent frailty terms. 6) Joint Nested frailty models in the context of the joint modelling for recurrent events with terminal event, for hierarchically clustered data (with two levels of clustering) by including two iid gamma random effects. 7) Multivariate joint frailty models for two types of recurrent events and a terminal event. 8) Joint models for longitudinal data and a terminal event. 9) Trivariate joint models for longitudinal data, recurrent events and a terminal event. 10) Joint frailty models for the validation of surrogate endpoints in multiple randomized clinical trials with failuretime endpoints Prediction values are available (for a terminal event or for a new recurrent event). Lefttruncated (not for Joint model), rightcensored data, intervalcensored data (only for Cox proportional hazard and shared frailty model) and strata are allowed. In each model, the random effects have the gamma or normal distribution. Now, you can also consider timevarying covariates effects in Cox, shared and joint frailty models (15). The package includes concordance measures for Cox proportional hazards models and for shared frailty models.
Maintainer:
Virginie Rondeau
Author(s): Virginie Rondeau, Juan R. Gonzalez, Yassin Mazroui, Audrey Mauguen, Amadou Diakite, Alexandre Laurent, Myriam Lopez, Agnieszka Krol and Casimir L. Sofeu
License: GPL (>= 2.0)
Uses: boot, doBy, MASS, nlme, statmod, survC1, survival, testthat, knitr, rmarkdown
Reverse suggests: icensBKL, reReg
Released 6 months ago.
55 previous versions
 frailtypack_3.0.3.1. Released 9 months ago.
 frailtypack_3.0.2.1. Released 11 months ago.
 frailtypack_3.0.2. Released 11 months ago.
 frailtypack_3.0.1. Released 12 months ago.
 frailtypack_2.13.2. Released about 1 year ago.
 frailtypack_2.13.1. Released about 1 year ago.
 frailtypack_2.12.7. Released over 1 year ago.
 frailtypack_2.12.6. Released about 2 years ago.
 frailtypack_2.12.5. Released about 2 years ago.
 frailtypack_2.12.4. Released about 2 years ago.
 frailtypack_2.12.3. Released over 2 years ago.
 frailtypack_2.12.2. Released over 2 years ago.
 frailtypack_2.12.1. Released over 2 years ago.
 frailtypack_2.11.1. Released over 2 years ago.
 frailtypack_2.11.0. Released over 2 years ago.
 frailtypack_2.10.5. Released almost 3 years ago.
 frailtypack_2.10.4. Released almost 3 years ago.
 frailtypack_2.10.3. Released about 3 years ago.
 frailtypack_2.9.4. Released over 3 years ago.
 frailtypack_2.9.3.1. Released over 3 years ago.
 frailtypack_2.9.3. Released over 3 years ago.
 frailtypack_2.8.3. Released almost 4 years ago.
 frailtypack_2.8.2. Released almost 4 years ago.
 frailtypack_2.8.1. Released almost 4 years ago.
 frailtypack_2.7.6.1. Released about 4 years ago.
 frailtypack_2.7.5. Released over 4 years ago.
 frailtypack_2.7.4. Released over 4 years ago.
 frailtypack_2.7.2. Released about 5 years ago.
 frailtypack_2.7.1. Released about 5 years ago.
 frailtypack_2.7. Released about 5 years ago.
 frailtypack_2.6.1. Released over 5 years ago.
 frailtypack_2.6. Released over 5 years ago.
 frailtypack_2.5.1. Released almost 6 years ago.
 frailtypack_2.5. Released almost 6 years ago.
 frailtypack_2.4.1. Released over 6 years ago.
 frailtypack_2.4. Released over 6 years ago.
 frailtypack_2.3. Released almost 7 years ago.
 frailtypack_2.227. Released almost 7 years ago.
 frailtypack_2.226. Released about 7 years ago.
 frailtypack_2.225. Released about 7 years ago.
 frailtypack_2.224. Released over 7 years ago.
 frailtypack_2.223. Released over 7 years ago.
 frailtypack_2.222. Released over 7 years ago.
 frailtypack_2.221. Released almost 8 years ago.
 frailtypack_2.220. Released about 8 years ago.
 frailtypack_2.219. Released about 8 years ago.
 frailtypack_2.218. Released about 8 years ago.
 frailtypack_2.217. Released over 8 years ago.
 frailtypack_2.216. Released about 9 years ago.
 frailtypack_2.214. Released over 9 years ago.
 frailtypack_2.213. Released over 9 years ago.
 frailtypack_2.212. Released almost 10 years ago.
 frailtypack_2.29.5. Released about 10 years ago.
 frailtypack_2.11. Released over 11 years ago.
 frailtypack_2.02. Released about 14 years ago.
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