mrgsolve (0.8.10)

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Simulate from ODE-Based Population PK/PD and Systems Pharmacology Models.

Facilitates simulation from hierarchical, ordinary differential equation (ODE) based models typically employed in drug development. A model specification file is created consisting of R and C++ code that is parsed, compiled, and dynamically loaded into the R session. Input data are passed in and simulated data are returned as R objects. A dosing event engine allows interventions (bolus and infusion) to be managed separately from the model code. Differential equations are solved with the 'DLSODA' routine in 'ODEPACK' ().

Maintainer: Kyle T Baron
Author(s): Kyle T Baron [aut, cre], Alan C Hindmarsh [ctb], Linda R Petzold [ctb], Bill Gillespie [ctb], Charles Margossian [ctb], Devin Pastoor [ctb], Metrum Research Group LLC [cph]

License: GPL (>= 2)

Uses: dplyr, lazyeval, magrittr, Rcpp, RcppArmadillo, tibble, XML, lattice, testthat, rmarkdown

Released 5 months ago.

3 previous versions



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