nph (2.0)

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Planning and Analysing Survival Studies under Non-Proportional Hazards.

Piecewise constant hazard functions are used to flexibly model survival distributions with non-proportional hazards and to simulate data from the specified distributions. Also, a function to calculate weighted log-rank tests for the comparison of two hazard functions is included. Finally, a function to calculate a test using the maximum of a set of test statistics from weighted log-rank tests is provided. This test utilizes the asymptotic multivariate normal joint distribution of the separate test statistics. The correlation is estimated from the data.

Maintainer: Robin Ristl
Author(s): Robin Ristl [aut, cre], Nicolas Ballarini [ctb]

License: GPL-3

Uses: ggplot2, mvtnorm, formatR, knitr, shiny, rmarkdown, shinycssloaders, styler

Released about 1 month ago.

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