openEBGM (0.8.2)

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EBGM Disproportionality Scores for Adverse Event Data Mining.

An implementation of DuMouchel's (1999) Bayesian data mining method for the market basket problem. Calculates Empirical Bayes Geometric Mean (EBGM) and quantile scores from the posterior distribution using the Gamma-Poisson Shrinker (GPS) model to find unusually large cell counts in large, sparse contingency tables. Can be used to find unusually high reporting rates of adverse events associated with products. In general, can be used to mine any database where the co-occurrence of two variables or items is of interest. Also calculates relative and proportional reporting ratios. Builds on the work of the 'PhViD' package, from which much of the code is derived. Some of the added features include stratification to adjust for confounding variables and data squashing to improve computational efficiency. Now includes an implementation of the EM algorithm for hyperparameter estimation loosely derived from the 'mederrRank' package.

Maintainer: John Ihrie
Author(s): John Ihrie [cre, aut], Travis Canida [aut], Ismal Ahmed [ctb] (author of 'PhViD' package (derived code)), Antoine Poncet [ctb] (author of 'PhViD'), Sergio Venturini [ctb] (author of 'mederrRank' package (derived code)), Jessica Myers [ctb] (author of 'mederrRank')

License: GPL-2 | GPL-3

Uses: data.table, ggplot2, DEoptim, testthat, knitr, dplyr, tidyr, rmarkdown

Released 9 months ago.

9 previous versions



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