phase1PRMD (1.0.1)

0 users

Personalized Repeated Measurement Design for Phase I Clinical Trials.

http://cran.r-project.org/web/packages/phase1PRMD

Implements Bayesian phase I repeated measurement design that accounts for multidimensional toxicity endpoints and longitudinal efficacy measure from multiple treatment cycles. The package provides flags to fit a variety of model-based phase I design, including 1 stage models with or without individualized dose modification, 3-stage models with or without individualized dose modification, etc. Functions are provided to recommend dosage selection based on the data collected in the available patient cohorts and to simulate trial characteristics given design parameters. Yin, Jun, et al. (2017) .

Maintainer: Lu Zhang
Author(s): Lu Zhang, Jun Yin

License: GPL (>= 2)

Uses: arrayhelpers, coda, dplyr, ggplot2, gridExtra, kableExtra, knitr, MASS, phase1RMD, plyr, RColorBrewer, reshape2, rjags

Released 9 months ago.


Ratings

Overall:

  (0 votes)

Documentation:

  (0 votes)

Log in to vote.

Reviews

No one has written a review of phase1PRMD yet. Want to be the first? Write one now.


Related packages:(20 best matches, based on common tags.)


Search for phase1PRMD on google, google scholar, r-help, r-devel.

Visit phase1PRMD on R Graphical Manual.