pocrm (0.12)

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Dose Finding in Drug Combination Phase I Trials Using PO-CRM.


Provides functions to implement and simulate the partial order continual reassessment method (PO-CRM) of Wages, Conaway and O'Quigley (2011) for use in Phase I trials of combinations of agents. Provides a function for generating a set of initial guesses (skeleton) for the toxicity probabilities at each combination that correspond to the set of possible orderings of the toxicity probabilities specified by the user.

Maintainer: "Varhegyi, Nikole E. (nev4g)"
Author(s): Nolan A. Wages

License: GPL-2

Uses: dfcrm, nnet

Released 11 months ago.

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