seqCBS (1.2.1)

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Copy Number Profiling using Sequencing and CBS.

This is a method for DNA Copy Number Profiling using Next-Generation Sequencing. It has new model and test statistics based on non-homogeneous Poisson Processes with change point models. It uses an adaptation of Circular Binary Segmentation. Also included are methods for point-wise Bayesian Confidence Interval and model selection method for the change-point model. A case and a control sample reads (normal and tumor) are required.

Maintainer: Jeremy J. Shen
Author(s): Jeremy J. Shen, Nancy R. Zhang

License: GPL-2

Uses: clue

Released about 1 year ago.

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