titeIR (0.1.0)

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Isotonic Designs for Phase 1 Trials with Late-Onset Toxicities.


Functions to design phase 1 trials using an isotonic regression based design incorporating time-to-event information. Simulation and design functions are available, which incorporate information about followup and DLTs, and apply isotonic regression to devise estimates of DLT probability.

Maintainer: Lee S. McDaniel
Author(s): Lee McDaniel [aut, cre]

License: GPL-3

Uses: Iso

Released about 1 year ago.



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