trialr (0.1.2)

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Clinical Trial Designs in 'rstan'.

https://github.com/brockk/trialr
http://cran.r-project.org/web/packages/trialr

A collection of clinical trial designs and methods, implemented in 'rstan' and R, including: the Continual Reassessment Method by O'Quigley et al. (1990) ; EffTox by Thall & Cook (2004) ; and the Augmented Binary method by Wason & Seaman (2013) ; and more. We provide functions to aid model-fitting and analysis. The 'rstan' implementations may also serve as a cookbook to anyone looking to extend or embellish these models. We hope that this package encourages the use of Bayesian methods in clinical trials. There is a preponderance of early phase trial designs because this is where Bayesian methods are used most. If there is a method you would like implemented, please get in touch.

Maintainer: Kristian Brock
Author(s): Kristian Brock [aut, cre] (<https://orcid.org/0000-0002-3921-0166>), Trustees of Columbia University [cph]

License: GPL (>= 3)

Uses: binom, coda, dplyr, ggplot2, gtools, magrittr, MASS, purrr, Rcpp, rlang, rstan, rstantools, stringr, tibble, tidybayes, tidyr, testthat, knitr, rmarkdown, DiagrammeR, covr, ggridges

Released 3 months ago.


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