trioGxE (0.1-1)

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A data smoothing approach to explore and test gene-environment interaction in case-parent trio data.

The package contains functions that 1) estimates gene-environment interaction between a SNP and a continuous non-genetic attribute by fitting a generalized additive model to case-parent trio data, 2) produces graphical displays of estimated interaction, 3) performs permutation test of gene-environment interaction; 4) simulates informative case-parent trios.

Maintainer: Ji-Hyung Shin
Author(s): Ji-Hyung Shin <>, Brad McNeney <>, Jinko Graham <>

License: GPL-2

Uses: gtools, mgcv, msm

Released over 6 years ago.



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