tag:crantastic.org,2005:/packages/wnlLatest activity for wnl2019-06-10T16:23:35Zcrantastic.orgtag:crantastic.org,2005:TimelineEvent/894482019-06-10T16:23:35Z2019-06-10T16:23:35Zwnl was upgraded to version 0.5.1<a href="/packages/wnl">wnl</a> was <span class="action">upgraded</span> to version <a href="/packages/wnl/versions/85039">0.5.1</a><br /><h3>Package description:</h3><p>This is a set of minimization tools (maximum likelihood estimation and least square fitting) to solve examples in the Johan Gabrielsson and Dan Weiner's book "Pharmacokinetic and Pharmacodynamic Data Analysis - Concepts and Applications" 5th ed. (ISBN:9198299107). Examples include linear and nonlinear compartmental model, turn-over model, single or multiple dosing bolus/infusion/oral models, allometry, toxicokinetics, reversible metabolism, in-vitro/in-vivo extrapolation, enterohepatic circulation, metabolite modeling, Emax model, inhibitory model, tolerance model, oscillating response model, enantiomer interaction model, effect compartment model, drug-drug interaction model, receptor occupancy model, and rebound phenomena model.</p>crantastic.orgtag:crantastic.org,2005:TimelineEvent/882172019-05-10T06:03:34Z2019-05-10T06:03:34Zwnl was upgraded to version 0.5.0<a href="/packages/wnl">wnl</a> was <span class="action">upgraded</span> to version <a href="/packages/wnl/versions/83882">0.5.0</a><br /><h3>Package description:</h3><p>This is a set of minimization tools (maximum likelihood estimation and least square fitting) to solve examples in the Johan Gabrielsson and Dan Weiner's book "Pharmacokinetic and Pharmacodynamic Data Analysis - Concepts and Applications" 5th ed. (ISBN:9198299107). Examples include linear and nonlinear compartmental model, turn-over model, single or multiple dosing bolus/infusion/oral models, allometry, toxicokinetics, reversible metabolism, in-vitro/in-vivo extrapolation, enterohepatic circulation, metabolite modeling, Emax model, inhibitory model, tolerance model, oscillating response model, enantiomer interaction model, effect compartment model, drug-drug interaction model, receptor occupancy model, and rebound phenomena model.</p>crantastic.orgtag:crantastic.org,2005:TimelineEvent/763492018-06-14T12:03:09Z2018-06-14T12:03:09Zwnl was upgraded to version 0.4.1<a href="/packages/wnl">wnl</a> was <span class="action">upgraded</span> to version <a href="/packages/wnl/versions/72854">0.4.1</a><br /><h3>Package description:</h3><p>This is a set of minimization tools (maximum likelihood estimation and least square fitting) to solve examples in the Johan Gabrielsson and Dan Weiner's book "Pharmacokinetic and Pharmacodynamic Data Analysis - Concepts and Applications" 5th ed. (ISBN:9198299107). Examples include linear and nonlinear compartmental model, turn-over model, single or multiple dosing bolus/infusion/oral models, allometry, toxicokinetics, reversible metabolism, in-vitro/in-vivo extrapolation, enterohepatic circulation, metabolite modeling, Emax model, inhibitory model, tolerance model, oscillating response model, enantiomer interaction model, effect compartment model, drug-drug interaction model, receptor occupancy model, and rebound phenomena model.</p>crantastic.orgtag:crantastic.org,2005:TimelineEvent/732552018-04-02T22:03:04Z2018-04-02T22:03:04Zwnl was upgraded to version 0.4.0<a href="/packages/wnl">wnl</a> was <span class="action">upgraded</span> to version <a href="/packages/wnl/versions/69937">0.4.0</a><br /><h3>Package description:</h3><p>This is a set of minimization tools (maximum likelihood estimation and least square fitting) to solve examples in the Johan Gabrielsson and Dan Weiner's book "Pharmacokinetic and Pharmacodynamic Data Analysis - Concepts and Applications" 5th ed. (ISBN:9198299107). Examples include linear and nonlinear compartmental model, turn-over model, single or multiple dosing bolus/infusion/oral models, allometry, toxicokinetics, reversible metabolism, in-vitro/in-vivo extrapolation, enterohepatic circulation, metabolite modeling, Emax model, inhibitory model, tolerance model, oscillating response model, enantiomer interaction model, effect compartment model, drug-drug interaction model, receptor occupancy model, and rebound phenomena model.</p>crantastic.orgtag:crantastic.org,2005:TimelineEvent/721062018-03-02T05:22:44Z2018-03-02T05:22:44Zwnl was upgraded to version 0.3.3<a href="/packages/wnl">wnl</a> was <span class="action">upgraded</span> to version <a href="/packages/wnl/versions/68855">0.3.3</a><br /><h3>Package description:</h3><p>This is a set of minimization tools (maximum likelihood estimation and least square fitting) to solve examples in the Johan Gabrielsson and Dan Weiner's book "Pharmacokinetic and Pharmacodynamic Data Analysis - Concepts and Applications" 5th ed. (ISBN:9198299107). Examples include linear and nonlinear compartmental model, turn-over model, single or multiple dosing bolus/infusion/oral models, allometry, toxicokinetics, reversible metabolism, in-vitro/in-vivo extrapolation, enterohepatic circulation, metabolite modeling, Emax model, inhibitory model, tolerance model, oscillating response model, enantiomer interaction model, effect compartment model, drug-drug interaction model, receptor occupancy model, and rebound phenomena model.</p>crantastic.orgtag:crantastic.org,2005:TimelineEvent/690552017-12-01T05:02:22Z2017-12-01T05:02:22Zwnl was upgraded to version 0.3.2<a href="/packages/wnl">wnl</a> was <span class="action">upgraded</span> to version <a href="/packages/wnl/versions/66015">0.3.2</a><br /><h3>Package description:</h3><p>This is a set of minimization tools (maximum likelihood estimation and least square fitting) to solve examples in the Johan Gabrielsson and Dan Weiner's book "Pharmacokinetic and Pharmacodynamic Data Analysis - Concepts and Applications" 5th ed. (ISBN:9198299107). Examples include linear and nonlinear compartmental model, turn-over model, single or multiple dosing bolus/infusion/oral models, allometry, toxicokinetics, reversible metabolism, in-vitro/in-vivo extrapolation, enterohepatic circulation, metabolite modeling, Emax model, inhibitory model, tolerance model, oscillating response model, enantiomer interaction model, effect compartment model, drug-drug interaction model, receptor occupancy model, and rebound phenomena model.</p>crantastic.orgtag:crantastic.org,2005:TimelineEvent/673912017-10-16T11:22:32Z2017-10-16T11:22:32Zwnl was released<a href="/packages/wnl">wnl</a> was <span class="action">released</span><br /><h3>Package description:</h3><p>This is a set of minimization tools (maximum likelihood estimation and least square fitting) to solve examples in the Johan Gabrielsson and Dan Weiner's book "Pharmacokinetic and Pharmacodynamic Data Analysis - Concepts and Applications" 5th ed. (ISBN:9198299107). Examples include linear and nonlinear compartmental model, turn-over model, single or multiple dosing bolus/infusion/oral models, allometry, toxicokinetics, reversible metabolism, in-vitro/in-vivo extrapolation, enterohepatic circulation, metabolite modeling, Emax model, inhibitory model, tolerance model, oscillating response model, enantiomer interaction model, effect compartment model, drug-drug interaction model, receptor occupancy model, and rebound phenomena model.</p>crantastic.org